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RESEARCH PAPER
Shift work, body mass index and associated breast cancer risks in postmenopausal women
1
Medical University, Łódź, Poland
2
University of Łódź, Poland
Corresponding author
Ann Agric Environ Med. 2023;30(4):699-704
KEYWORDS
TOPICS
Prevention of occupational diseases in agriculture, forestry, food industry and wood industryState of the health of rural communities depending on various factors: social factors, accessibility of medical care, etc.
ABSTRACT
Introduction and objective:
Shift work increases the risk of breast cancer, but the mechanisms is still under discussion. This study evaluates the relationship between breast cancer and shift work on the basis of overweight and obesity among postmenopausal women.
Material and methods:
We examined this association using data from a case–control study carried between 2015 and 2019. The study involved 111 postmenopausal women with breast cancer and the same number of control participants. A self-reporting questionnaire was used for data collection. Multivariate logistic regression was conducted to find correlations between variables and determine the strength of relationships.
Results:
A 2.65-fold risk of breast cancer (OR=2.65; 95% CI: 1.34–5.22) was found among shift work women, compared with postmenopausal women not performing shift work. The association was modified by body mass index, showing a risk rate 9.84 times higher (OR=9.84; 95% CI: 2.14–45.19) among shift work and overweight women, compared to non-overweight women who had never been shift workers.
Conclusions:
About 49% of controls and 72% of cases had ever worked in a job that required shift work. The risk of breast cancer in postmenopausal women is associated with shift work, especially among overweight women. Some preventive measures to reduce the risk of breast cancer, in particular regarding a healthy lifestyle and weight control in this group of working women, should be implemented.
Shift work increases the risk of breast cancer, but the mechanisms is still under discussion. This study evaluates the relationship between breast cancer and shift work on the basis of overweight and obesity among postmenopausal women.
Material and methods:
We examined this association using data from a case–control study carried between 2015 and 2019. The study involved 111 postmenopausal women with breast cancer and the same number of control participants. A self-reporting questionnaire was used for data collection. Multivariate logistic regression was conducted to find correlations between variables and determine the strength of relationships.
Results:
A 2.65-fold risk of breast cancer (OR=2.65; 95% CI: 1.34–5.22) was found among shift work women, compared with postmenopausal women not performing shift work. The association was modified by body mass index, showing a risk rate 9.84 times higher (OR=9.84; 95% CI: 2.14–45.19) among shift work and overweight women, compared to non-overweight women who had never been shift workers.
Conclusions:
About 49% of controls and 72% of cases had ever worked in a job that required shift work. The risk of breast cancer in postmenopausal women is associated with shift work, especially among overweight women. Some preventive measures to reduce the risk of breast cancer, in particular regarding a healthy lifestyle and weight control in this group of working women, should be implemented.
ACKNOWLEDGEMENTS
This research was supported by the funds for the development
of young researchers and Ph.D. students at the Medical
University of Lodz (502-03/6-024-0/502-64-100-18) and co-
financed by Medical University of Lodz (503/6-024-01/503-
66-001 and 503/6-024-01/503-61-001-19-00).
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