Online first
Current issue
Archive
Special Issues
About the Journal
Publication Ethics
Anti-Plagiarism system
Instructions for Authors
Instructions for Reviewers
Editorial Board
Editorial Office
Contact
Reviewers
All Reviewers
2023
2022
2021
2020
2019
2018
2017
2016
General Data Protection Regulation (RODO)
RESEARCH PAPER
Selected non-somatic risk factors for pregnancy loss in patients with abnormal early pregnancy
1
3rd Department of Gynecology, Medical University of Lublin, Poland
2
Department of Oncology, Medical University of Lublin, Poland
Ann Agric Environ Med. 2016;23(1):153-156
KEYWORDS
ABSTRACT
Introduction and objective:
Spontaneous abortion constitutes one of the most frequent complication of human pregnancy. Despite intensive research efforts undertaken to date, the etiopathogenesis of early pregnancy loss has not been fully elucidated. The objective of this study was to analyze the role of selected non-somatic risk factors for early pregnancy loss in patients with various clinical manifestations of spontaneous abortion.
Material and Methods:
The study included 242 women hospitalized between 2001 and 2004 in the 3rd Chair and Department of Gynecology, Medical University of Lublin, Poland (Teaching Hospital No.4) with various clinical categories of spontaneous abortion. Each patient completed a questionnaire assessing her exposure to the examined factors. In patients with threatened abortion dismissed from the hospital with viable gestation, the course of pregnancy was followed-up using questionnaire data and medical records.
Results:
In the studied population of women with abnormal early pregnancy course, a significant impact on the risk of miscarriage was observed in case of such factors as: exposure to stress at home and limited number of hours of nightly sleep. Factors such as occupational hazards, diet, stress, heavy housework and use of cigarettes or alcohol did not exert a significant effect on the risk of miscarriage in the studied population.
Conclusions:
The results of this study confirm the complexity of the early pregnancy loss etiopatogenesis. Further research need to be conducted in order to identify the non-somatic causative agents of various clinical forms of miscarriage. It may help do select women in reproductive age at high risk of early pregnancy loss and show the ways in which effective preventive measures can be introduced in such population.
Spontaneous abortion constitutes one of the most frequent complication of human pregnancy. Despite intensive research efforts undertaken to date, the etiopathogenesis of early pregnancy loss has not been fully elucidated. The objective of this study was to analyze the role of selected non-somatic risk factors for early pregnancy loss in patients with various clinical manifestations of spontaneous abortion.
Material and Methods:
The study included 242 women hospitalized between 2001 and 2004 in the 3rd Chair and Department of Gynecology, Medical University of Lublin, Poland (Teaching Hospital No.4) with various clinical categories of spontaneous abortion. Each patient completed a questionnaire assessing her exposure to the examined factors. In patients with threatened abortion dismissed from the hospital with viable gestation, the course of pregnancy was followed-up using questionnaire data and medical records.
Results:
In the studied population of women with abnormal early pregnancy course, a significant impact on the risk of miscarriage was observed in case of such factors as: exposure to stress at home and limited number of hours of nightly sleep. Factors such as occupational hazards, diet, stress, heavy housework and use of cigarettes or alcohol did not exert a significant effect on the risk of miscarriage in the studied population.
Conclusions:
The results of this study confirm the complexity of the early pregnancy loss etiopatogenesis. Further research need to be conducted in order to identify the non-somatic causative agents of various clinical forms of miscarriage. It may help do select women in reproductive age at high risk of early pregnancy loss and show the ways in which effective preventive measures can be introduced in such population.
REFERENCES (25)
1.
WHO recommended definitions, terminology and format for statistical tables related to the perinatal period and use of a new certificate for cause of perinatal deaths. Modifications recommended by FIGO as amended October 14, 1976. Acta Obstet Gynecol Scand. 1977; 56(3): 247–253.
2.
Wendt K, Crilly J, May C, Bates K, Saxena R. An outcomes evaluation of an emergency department early pregnancy assessment service and early pregnancy assessment protocol. Emerg Med J. 2013; 17(7): 567–578.
3.
Coste J, Job-Spira N, Fernandez H. Risk factors for spontaneous abortion: a case control study in France. Hum Reprod. 1991; 6(9): 1332–1337.
4.
Stephenson M. Frequency of factors associated with habitual abortion in 197 couples. Fertil Steril. 1996; 66(1): 24–29.
5.
Stern JJ, Dorfmann AD, Gutierrez-Najar AJ, Cerrillo M, Coulam CB. Frequency of abnormal karyotype among abortus from women with and without a history of spontaneous abotrion. Fertil Steril. 1996; 65(2): 250–253.
6.
Alimohamadi S, Javadian P. Progesterone and threatened abortion: a randomized clinical trial on endocervical cytokine concentrations. J Reprod Immunol. 2013; 98(2): 52–60.
7.
Gu CH, Liang WJ, Fu LL, Zheng LW. Risk factors of recurrent spontaneous abortion. Nat J Androl. 2013; 19(8): 758–762.
8.
Armstrong BG, McDonald AD, Sloan M. Cigarette, Alcohol and Coffee Consumption and Spontaneous Abortion. Am J Public Health. 1992; 82(1): 85–87.
9.
Di Cintio E, Parazzini F, Chatenoud L, Surace H, Benzi G, Zanconato G, et al. Dietary factors and risk of spontaneous abortion. Eur J Obstet Gynecol. 2001; 95(1): 132–136.
10.
Jauniaux E, Van Oppenraaij RH, Burton GJ. Obstetric outcome after early placental complications. Curr Opin Obstet Gynecol. 2010; 22(6): 452–457.
11.
Frank P, McNamee R, Hannaford PC, Kay CR. Effect of changes in maternal smoking habits in early pregnancy on infant birthweight. Br J Gen Pract. 1994; 44(379): 57–59.
12.
Kubicki J. Wpływ palenia tytoniu na stan płodu. Ginekol Pol. 1991; 62(3): 488–493.
13.
Windham GH, Swan SH, Fenster L. Parental cigarette smoking and the risk of spontaneous abortion. Am J Epidemiol. 1992; 135(12): 1394–1403.
14.
Maximovich P, Beyler SA. Cigarette smoking at time of in vivo fertilization cycle initiation has negative effect on in vitro fertilization-embryo transfer success rate. J Assist Reprod Genet. 1995; 12(2): 75–79.
15.
Buss L, Tolstrup J, Munk C, Bergholt T, Ottensen B, Gronbaek M, et al. Spontaneous abortion: a prospective cohort study of younger women from the general population in Denmark. Validation, occurrence and risk determinants. Acta Obstet Gynecol Scand. 2006; 85(4): 467–475.
16.
Sackoff J, Kline J, Susser M. Previous use of oral contraceptive and spontaneous abortion. Epidemiology. 1994; 5(4): 422–428.
17.
George L, Granarh F, Johannson AL. Environmental tobacco smoke and risk of spontaneous abortion. Epidemiology. 2006; 17(4): 492–494.
18.
Meeker J, Benedict M. Infertility, Pregnancy Loss and Adverse Birth Outcomes in Relation to Maternal Secondhand Tobacco Smoke Exposure. Curr Womens Health Rev. 2013; 9(1): 41–49.
19.
Regan L, Rai R. Epidemiology and the medical causes of miscarriage. Clin Obstet Gynaecol. 2000; 14(5): 839–845.
20.
Fenster L, Hubbard AE, Windham GC, Waller KO, Swan SH. A prospective study of work-related physical exertion and spontaneous abortion. Epidemiology. 1997; 8(1): 66–74.
21.
Savitz DA, Brett K, Dole N, Tse CK. Male and female occupation in relation to miscarriage and preterm delivery in central North Carolina. Ann Epidemiol. 1997; 7(7): 509–516.
22.
Schlunssen V, Viskum S, Omland O, Bonde JP. Does shift work cause spontaneous abortion, preterm birth or low birth weight? Dan Med J. 2007; 169(10): 893–900.
23.
Nielsen C, Brandt L. Fetal growth, preterm birth and infant mortality in relation to work with video display terminals during pregnancy. Scand J Work Environ Health. 1992; 18(6): 346–350.
24.
Garcia C, Sammel M, Chittams J, Hummel AC, Shaunika A, et al. Risk factors for spontaneous abortion in Early symptomatic first trimester pregnancies. Obstet Gynecol. 2005; 106(5): 993–999.
25.
Johns J, Janiaux E. Threatened miscarriage as a predictor of obstetric outcome. Obstet Gyneacol. 2006; 107(4): 845–850.
Share
RELATED ARTICLE
| eISSN: | 1898-2263 |
| ISSN: | 1232-1966 |
Improvement of visual identification of the journal - task financed under the agreement No. 618/P-DUN/2019 by the Minister of Science and Higher Education allocated to the activities of disseminating science.
Generation of the DOI (Digital Object Identifier) - task financed under the agreement No. 618/P-DUN/2019 by the Minister of Science and Higher
© 2006-2024 Journal hosting platform by Bentus
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
