The aims were to examine the prevalence of stress among Finnish full-time farm entrepreneurs in 2004 (n = 1,182) and to compare the results with those for the general working population in 2003. The second aim was to analyze which factors were associated with the prevalence of stress. A stratified random sample of farm entrepreneurs gathered from the farm register was surveyed using computer-assisted telephone interviews. A binary logistic regression model was used to analyze the association with background factors. One third (34%) of the examined farmers had experienced stress. This amount was lower than among the general working population (44%). The most common factors associated with farmers’ stress were problems in social family relationships and mental support. Physical factors such as the strenuousness of agricultural work, illness and a low estimation of their own working ability, were also related to stress. Increased stress was also associated with economic problems. Health and extension services should pay special attention to encouraging farm entrepreneurs to maintain their social relationships. The relatively low level of stress observed may indicate that those who have continued within the agricultural sector have the psychological capacity to deal with stressful situations.