CASE REPORT
Insect bites as a trigger factor of eosinophilic cellulitis
 
More details
Hide details
1
Faculty of Medicine, Jan Kochanowski University, Kielce, Poland
 
2
Dermatology Department, Provincial General Hospital, Kielce, Poland
 
 
Corresponding author
Monika Kucharczyk   

Jan Kochanowski University, The faculty od Medicine, IX Wieków Kielc 19, 25-317 Kielce, Poland
 
 
Ann Agric Environ Med. 2019;26(2):256-259
 
KEYWORDS
TOPICS
ABSTRACT
Introduction:
The study presents the case report of a Wells Syndrome in a 18-year -ld female. Wells Syndrome is a rare inflammatory skin disorder which seems to present an abnormal eosinophilic response to a number of triggers.

Objective:
The aim of the study is to discuss several problems related to the diagnosis and treatment of Wells Syndrome.

Material and Methods:
Medical examination, blood tests, abdominal ultrasound and skin biopsy were performed.

Results:
Medical examination revealed plaques with tense blisters on feet and erythematous lesions on trunk. Blood tests showed raised anti-streptolysin O level. Skin biopsy revealed features of eosinophilic cellulitis. Oral administration of 0.5 mg per day prednisolone and antihistaminics with local therapy resulted in good clinical response.

Conclusions:
Sometimes several biopsy are required to establish diagnosis. In some cases lower doses of corticosteroids with antihistaminics and local anti-inflammatory treatment can by sufficient in treatment.

ACKNOWLEDGEMENTS
The authors express their thanks dr Janusz Kopczyński for the microscopic photos.
REFERENCES (18)
1.
Räßler F, Lukács J, Elsner P. Treatment of Eosinophilic Cellulitis (Wells Syndrome) – a Systematic Review. J Eur Acad Dermatol Venereol. 2016; 30(9): 1465–79.
 
2.
Ferreli C, Pinna AL, Atzori L, Aste N. Eosinophilic Cellulitis (Wells’ Syndrome): A New Case Description. J Eur Acad Dermatol Venereol. 1999; 13(1): 41–45.
 
3.
Fisher GB, Greer KE, Cooper PH. Eosinophilic Cellulitis (Wells’ Syndrome). Int J Dermatol. 1985; 24(2): 101–107.
 
4.
Bolognia JL, Schaffer JV, Cerroni L, Dermatology. 4 ed. Elsevier, 2017.
 
5.
Aberer W, Konrad K, Wolff K. Wells’ Syndrome Is a Distinctive Disease Entity and Not a Histologic Diagnosis. J Eur Acad Dermatol. 1988; 18 (1Pt 1): 105–14.
 
6.
Schuttelaar M.-La, Jonkman MF. Bullous Eosinophilic Cellulitis (Wells’ Syndrome) Associated with Churg–Strauss Syndrome. J Eur Acad Dermatol. 2003; 17(1): 91–93.
 
7.
Heelan K, Ryan JF, Shear NH, Egan CA. Wells syndrome (eosinophilic cellulitis): Proposed diagnostic criteria and a literature review of the drug-induced variant. J Dermatol Case Rep. 2013; 7(4): 113–20.
 
8.
Simon HU, Plötz S, Simon D, Seitzer U, Braathen LR, Menz G, Straumann A, Dummer R, LeviSchaffer F. Interleukin-2 Primes Eosinophil Degranulation in Hypereosinophilia and Wells’ Syndrome. Eur J Immunol. 2003; 33(4): 834–39.
 
9.
Nielsen T, Schmidt H, Søgaard H. Eosinophilic Cellulitis. (Well’s Syndrome) in a Child. Arch Dermatol. 198l; 117(7): 427–9.
 
10.
Caputo R, Marzano AV, Vezzoli P, Lunardon L. Wells syndrome in adults and children: a report of 19 cases. Arch Dermatol. 2006; 142(9): 1157–61.
 
11.
Anhi Lee. Eosinophilic Cellulitis (Wells’ Syndrome). Korean J Pathol. 1995; 29(3): 407–10.
 
12.
Sinno H, Lacroix JP, Lee J, Izadpanah A, Borsuk R, Watters K, Gilardino M. Diagnosis and Management of Eosinophilic Cellulitis (Wells’ Syndrome): A Case Series and Literature Review. Can J Plast Surg. 2012; 20(2): 91–7.
 
13.
Schwartz RA. Wells Syndrome: Background, Pathophysiology, Etiology. Medscape https://emedicine.medscape.com... (access 2018).
 
14.
Nacaroglu HT, Celegen M, Karkıner CS, Günay I, Diniz G, Can D. Eosinophilic cellulitis (Wells’ syndrome) caused by a temporary henna tattoo Postępy Dermatol Alergol. 2014; 31(5): 322–4 31.
 
15.
Goh CL. Eosinophilic Cellulitis (Wells’syndrome). Int J Dermatol. 1992; 31(6): 429–30.
 
16.
Tassava T, Rusonis PA, Whitmore SE. Recurrent Vesiculobullous Plaques. Eosinophilic Cellulitis (Wells Syndrome). Arch Dermatol. 1997; 133(12): 1580–1, 1583–4.
 
17.
Gilliam AE, Bruckner AL, Howard RM, Lee BP, Wu S, Frieden IJ. Bullous ”cellulitis” with eosinophilia: case report and review of Wells’ syndrome in childhood. Pediatrics. 2005; 116(1): e14955.
 
18.
Coldiron BM, Robinson JK. Low-Dose Alternate-Day Prednisone for Persistent Wells’ Syndrome. Arch Dermatol. 1989; 125(12): 1625–6.
 
eISSN:1898-2263
ISSN:1232-1966
Journals System - logo
Scroll to top