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1/2012 vol. 19
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RESEARCH PAPER
Influence of environment exposures on the frequency of contact allergies in children and adolescents
Ewa Czarnobilska 1
,
 
Wojciech Dyga 1
,
 
Diana Krzystyniak 2
,
 
Krzysztof Czarnobilski 3
,
 
Dorota Myszkowska 1
,
 
Krystyna Obtułowicz 1
 
 
 
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1
Department of Clinical and Environmental Allergology, Faculty of Medicine, Jagiellonian University, Krakow, Poland
 
2
St. Louis Children\'s Hospital, Krakow, Poland
 
3
Ministry of Internal Affairs and Administration (MSWiA) Hospital, Krakow, Poland
 
 
Ann Agric Environ Med. 2012;19(1):11-16
 
Article (PDF)
References (55)
 
KEYWORDS
contact allergy
patch tests
nickel
propolis
fragrance mix
thimerosal
Kathon CG
children
 
ABSTRACT
Contact allergy is detected in every second child with the symptoms of chronic or recurrent eczema, and in every third child the final diagnosis is allergic contact dermatitis. Haptens responsible for the majority of contact sensitizations in children are substances ubiquitous in our environment, e.g. metals, preservatives, fragrances, propolis, and balsam of Peru. Much concern is provoked by the higher rates of sensitization to fragrances in younger children, compared to adolescents, which may be attributed to the higher exposure nowadays of infants and children to fragrant products. On the other hand, a limitation of exposure to the preservatives thimerosal and Kathon CG has resulted in decreased rates of sensitization to these haptens. Altogether, these observations demonstrate that the rates of contact sensitizations in children reflect changes in their environment, and limitations imposed on the use of haptens with strong sensitizing properties, may be an effective tool in the prevention of contact allergy.
 
REFERENCES (55)
1.
Czarnobilska E, Obtułowicz K, Wsołek K, Piętowska J, Śpiewak R. Mechanisms of nickel allergy. Przegl Lek. 2007; 64: 502-505.
Google Scholar
 
 
2.
Czarnobilska E, Obtułowicz K, Wsołek K. Type IV hypersensitivity reaction and its subtypes. Przegl Lek. 2007; 64: 506-508.
Google Scholar
 
 
3.
Śpiewak R, Piętowska J, Curzytek K. Nickel – a unique allergen. From molecular structure to European legislation. Expert Rev Clin Immunol. 2007; 3: 851-859.
Google Scholar
 
 
4.
Czarnobilska E, Jenner B, Kapusta M, Obtulowicz K, Curzytek K, Thor P, Spiewak R. The role of Interleukin-5 and Interferon-gamma in the pathomechanism of allergic contact dermatitis to nickel. J Physiol Pharmacol. 2007; 58(Suppl 4): 68.
Google Scholar
 
 
5.
Czarnobilska E, Jenner B, Kapusta M, Obtulowicz K, Thor P, Spiewak R. Contact allergy to nickel: Patch test score correlates with IL-5, but not with IFN-? nickel-specific secretion by peripheral blood lymphocytes. Ann Agric Environ Med. 2009; 16: 37-41.
Google Scholar
 
 
6.
Czarnobilska E, Thor P, Kaszuba-Zwoinska J, Obtułowicz K. Correlation between patch test results and antigen-specific cytokine secretion in nickel-allergic patients. XXV EAACI Congress, 12-16 June 2006, Vienna, Abstract Book, 293.
Google Scholar
 
 
7.
Czarnobilska E, Thor P, Kaszuba-Zwoinska J, Słodowska-Hajduk Z, Kapusta M, Stobiecki M, Dyga W, Wsołek K, Obtułowicz K. Response of peripheral blood mononuclear leukocytes to nickel stimulation in patients with systemic and contact allergy to nickel. Przegl Lek. 2006; 63: 1276-1280.
Google Scholar
 
 
8.
Śpiewak R, Brewczyński PZ. Powikłania po stabilizacji płytą metalową złamania kości udowej u chorej z alergią kontaktową na chrom, nikiel i kobalt. [Complications after metal plate stabilization of femoral fracture in a female patient with contact hypersensitivity to chromium, nickel and kobalt]. Pol Tyg Lek. 1993; 48: 651-652.
Google Scholar
 
 
9.
Thyssen JP, Uter W, McFadden J, Menne T, Śpiewak R, Vigan M, Gimenez-Arnau A, Liden C. The EU Nickel Directive revisited – future steps towards better protection against nickel allergy. Contact Dermatitis. 2011; 64: 121-125.
Google Scholar
 
 
10.
Czarnobilska E, Łach K, Odrzywołek L, Śliwa Ł, Wsołek-Wnęk K, Obtułowicz K, Śpiewak R. Detection of contact allergy: Using more extensive test series increases the diagnostic efficacy of patch tests. Przegl Lek. 2010; 67: 103-106.
Google Scholar
 
 
11.
Śpiewak R. Alergia kontaktowa – diagnostyka i postępowanie. [Contact allergy – diagnosis and treatment] Alergia Astma Immunologia. 2007; 12: 109-126.
Google Scholar
 
 
12.
Śpiewak R. Patch testing for contact allergy and allergic contact dermatitis. Open Allergy J. 2008; 1: 42-51.
CrossRef
 
Google Scholar
 
 
13.
Śpiewak R. Wyprysk kontaktowy. [Contact eczema] Post Dermatol Alergol. 2009; 26: 375-377.
Google Scholar
 
 
14.
Bruze M, Andersen KE, Goossens A ESCD; EECDRG: Recommendation to include fragrance mix 2 and hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral) in the European baseline patch test series. Contact Dermatitis 2008; 58: 129-33.
Google Scholar
 
 
15.
Roul S. Usefulness of the European standard series for patch testing in children. A 3-year single-centre study of 337 patients. Contact Dermatitis. 1999; 40: 232-235.
CrossRef
 
Google Scholar
 
 
16.
Bonitsis NG, Tatsioni A, Bassioukas K, Ioannidis JP. Allergens responsible for allergic contact dermatitis among children: a systematic review and meta-analysis. Contact Dermatitis. 2011; 64: 245-257.
CrossRef
 
Google Scholar
 
 
17.
Czarnobilska E, Obtułowicz K, Dyga W, Śpiewak R. A half of schoolchildren with ‘ISAAC eczema’ are ill with allergic contact dermatitis. J Eur Acad Dermatol Venereol 2011, DOI: 10.1111/j.1468-3083.2010.03885.x (Epub ahead of print).
CrossRef
 
Google Scholar
 
 
18.
Śpiewak R. Allergic contact dermatitis in childhood – a review and meta-analysis. Allergologie 2002; 25: 374-381.
CrossRef
 
Google Scholar
 
 
19.
Czarnobilska E, Obtulowicz K, Dyga W, Spiewak R. The most important contact sensitizers in Polish children and adolescents with atopy and chronic recurrent eczema as detected with the extended European Baseline Series. Pediatr Allergy Immunol. 2011; 22: 252-256.
Google Scholar
 
 
20.
Czarnobilska E, Obtulowicz K, Dyga W, Wsołek-Wnęk K, Spiewak R. Contact hypersensitivity and allergic contact dermatitis among schoolchildren and teenagers with eczema. Contact Dermatitis. 2009; 60: 264-269.
Google Scholar
 
 
21.
Lee PW, Elsaie ML, Jacob SE. Allergic contact dermatitis in children: common allergens and treatment: a review. Curr Opin Pediatr. 2009; 21: 491-498.
Google Scholar
 
 
22.
Beattie PE, Green C, Lowe G, Lewis-Jones MS. Which children should we patch test? Clin Exp Dermatol. 2007; 32: 6-11.
Google Scholar
 
 
23.
Clayton TH, Wilkinson SM, Rawcliffe C, Pollock B, Clark SM. Allergic contact dermatitis in children: should pattern of dermatitis determine referral? A retrospective study of 500 children tested between 1995 and 2004 in one UK centre. Br J Dermatol. 2006; 154: 114-117.
Google Scholar
 
 
24.
Onder M, Adisen E. Patch test results in a Turkish paediatric population. Contact Dermatitis. 2008; 58: 63-65.
Google Scholar
 
 
25.
Jacob SE, Moennich JN, McKean BA, Zirwas MJ, Taylor JS. Nickel allergy in the United States: a public health issue in need of a ‘nickel directive’. J Am Acad Dermatol. 2009; 60: 1067-1069.
CrossRef
 
Google Scholar
 
 
26.
Nguyen SH, Dang TP, MacPherson C, Maibach H, Maibach HI. revalence of patch test results from 1970 to 2002 in a multi-centre population in North America (NACDG). Contact Dermatitis. 2008; 58: 101-106.
Google Scholar
 
 
27.
Pratt MD, Belsito DV, DeLeo VA, Fowler JF Jr, Fransway AF, Maibach HI, Marks JG, Mathias CG, Rietschel RL, Sasseville D, Sherertz EF, Storrs FJ, Taylor JS, Zug K. N Am Contact Dermatitis Group patch-test results, 2001-2002 study period. In: Dermatitis. 2004; 15: 176-183. Erratum in: Dermatitis. 2005; 16: 106.
Google Scholar
 
 
28.
Smith-Sivertsen T, Dotterud LK, Lund E. Nickel allergy and its relationship with local nickel pollution, ear piercing, and atopic dermatitis: a population-based study from Norway. J Am Acad Dermatol. 1999; 40: 726-735.
Google Scholar
 
 
29.
Jensen CS, Lisby S, Baadsgaard O, Volund A, Menne T. Decrease in nickel sensitization in a Danish schoolgirl population with ears pierced after implementation of a nickel-exposure regulation. Br J Dermatol. 2002; 146: 636-642.
Google Scholar
 
 
30.
Thyssen J, Menne T, Liden C, White I, White J, Spiewak R, Johansen J. Excessive nickel release from earrings purchased from independent shops and street markets – a field study from Warsaw and London. J Eur Acad Dermatol Venereol 2011, DOI: 10.1111/j.1468-3083.2010.03909.x. (Epub ahead of print).
CrossRef
 
Google Scholar
 
 
31.
Thyssen JP, Johansen JD, Menné T. Contact allergy epidemics and their controls. Contact Dermatitis. 2007; 56: 185-195.
Google Scholar
 
 
32.
Śpiewak R, Piętowska J. Nikiel – alergen wyjątkowy. Od struktury atomu do regulacji prawnych [Nickel – the unique allergen. From molecular structure to legal regulations]. Alergol Immunol. 2006; 3: 58-62.
Google Scholar
 
 
33.
Wöhrl S, Jandl T, Stingl G, Kinaciyan T. Cellular phone addiction and allergic contact dermatitis to nickel. Mobile telephone as new source for nickel dermatitis. Contact Dermatitis. 2007; 56: 113.
Google Scholar
 
 
34.
Sławeta G, Kieć-Świerczyńska M. Alergia kontaktowa u młodzieży kończącej szkołę podstawową. Przegl Dermatol. 1999; 86: 143-147.
Google Scholar
 
 
35.
Śpiewak R. Atopy and contact hypersensitivity: a reassessment of the relationship using objective measures. Ann Allergy Asthma Immunol. 2005; 95: 61-65.
Google Scholar
 
 
36.
Rebandel P, Rudzki E. Jednoczesne uczulenie na nikiel i pallad. [Simultaneous allergy to nickel and palladium] Przegl Dermatol. 1990; 77: 255-258.
Google Scholar
 
 
37.
Rudzki E, Rebandel P. Contact dermatitis in children. Contact Dermatitis. 1996; 34: 66-67.
Google Scholar
 
 
38.
Czarnobilska E, Dyga W, Obtułowicz A, Obtułowicz K, Śpiewak R. Contact allergy among Polish children and adolescents with dermatitis. Contact Dermatitis. 2008; 58: 24-25.
Google Scholar
 
 
39.
Czarnobilska E, Spiewak R, Dyga W, Obtulowicz A, Wsolek-Wnek K, Obtułowicz K. Contact allergy among Polish children and adolescents with dermatitis. Alergia Astma Immunol. 2008; 13: 100-109.
Google Scholar
 
 
40.
Copeland SD, DeBey S, Hutchison D. Nickel allergies: implications for practice. Dermatol Nurs. 2007; 19: 267-288.
Google Scholar
 
 
41.
Czarnobilska E, Klimaszewska-Rembiasz M, Gaweł B, Obtułowicz K. Występowanie chorób alergicznych u dzieci w szkołach podstawowych Krakowa i okolic – próba określenia głównych czynników ryzyka. [Prevalence of allergic diseases in primary school children in Cracow and surroundings – risk factors] Przegl Lek. 2002; 59: 422-426.
Google Scholar
 
 
42.
Kütting B, Brehler R, Traupe H. Allergic contact dermatitis in children: strategies of prevention and risk management. Eur J Dermatol. 2004; 14: 80-85.
Google Scholar
 
 
43.
Vigan M. Usefulness of the European standard series for patch testing in children. Contact Dermatitis. 2008; 58(Suppl 1): 24.
Google Scholar
 
 
44.
Mortz CG, Lauritsen JM, Bindslev-Jensen C, Andersen KE. Nickel sensitization in adolescents and association with ear piercing, use of dental braces and hand eczema. The Odense Adolescence Cohort Study on Atopic Diseases and Dermatitis (TOACS). Acta Derm Venereol. 2002; 82: 359-364.
Google Scholar
 
 
45.
Śpiewak R. Immunotherapy of allergic contact dermatitis. Immunotherapy. 2011; 3: 979-996.
Google Scholar
 
 
46.
Śpiewak R. Alergia kontaktowa i alergiczny wyprysk kontaktowy. In: Fal AM (Ed.): Alergia, choroby alergiczne, astma. Med Prak, Kraków. 2011; 371-391.
Google Scholar
 
 
47.
Śpiewak R. Positive patch tests to palladium are not mere cross-reactivities to nickel but relevant diagnostic findings. Allergy. 2011; 66(Suppl 94): 689-690.
Google Scholar
 
 
48.
Lerbaek A, Kyvik KO, Menné T, Agner T, Livideanu C, Giordano-Labadie F, Paul C. Retesting with the TRUE Test in a population-based twin cohort with hand eczema – allergies and persistence in an 8-year follow-up study. Contact Dermatitis. 2007; 57: 248-252.
Google Scholar
 
 
49.
Hausen BM. Evaluation of the main contact allergens in propolis (1995 to 2005). Dermatitis. 2005; 16: 127-129.
Google Scholar
 
 
50.
Pietowska J, Czarnobilska E, Spiewak R; The most frequent contact sensitizers and atopic diseases among consecutive patients of a Polish patch test clinic. Allergy. 2008; 63(Suppl 88): 320.
Google Scholar
 
 
51.
Heine G, Schnuch A, Uter W, Worm M. Frequency of contact allergy in German children and adolescents patch tested between 1995 and 2002: results from the Information Network of Departments of Dermatology and the German Contact Dermatitis Research Group. Contact Dermatitis. 2004; 51: 111-117.
Google Scholar
 
 
52.
Militello G, Jacob SE, Crawford GH. Allergic contact dermatitis in children. Curr Opin Pediatr. 2006; 18: 385-390.
Google Scholar
 
 
53.
Freiman A, Al-Layali A, Sasseville D. Patch testing with thimerosal in a Canadian center: an 11-year experience. Am J Contact Dermat. 2003; 14: 138-143.
Google Scholar
 
 
54.
Wattanakrai P, Rajatanavin N. Thimerosal allergy and clinical relevance in Thailand. J Med Assoc Thai. 2007; 90: 1775-1779.
Google Scholar
 
 
55.
Seidenari S, Giusti F, Pepe P, Mantovani L. Contact sensitization in 1,094 children undergoing patch testing over a 7-year period. Pediatr Dermatol. 2005; 22: 1-5.
Google Scholar
 
 
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