Chair and Department of Pneumonology, Oncology and Allergology, Medical University, Lublin, Poland
2
Chair of Internal Medicine and Department of Internal Medicine in Nursing, Medical University, Lublin, Poland
3
1st Department of Radiology, Medical University, Lublin, Poland
4
Chair and Department of Rheumatology and Connective Tissue Diseases, Medical University, Lublin, Poland
Corresponding author
Anna Grzywa-Celińska
Chair and Department of Pneumonology, Oncology and Allergology, Medical University , Lublin., ul. Jaczewskiego 8, 20-954, Lublin, Poland
Introduction. During the Coronavirus-19 (Covid-19) pandemic, a significant increase in the frequency of complications in
the form of venous thrombosis was observed. However, there is also the other side of the coin – an increase in the tendency
to bleeding in the course of COVID19.
Case Report. We present the case of a patient hospitalised in the COVID-19 Isolation Ward due to severe pneumonia in
the course of SARS-CoV2 infection. She developed respiratory failure requiring a non-invasive mechanical ventilation. In
addition, pulmonary embolism was diagnosed, the treatment with low molecule heparin was initiated. Soon, the patient
developed a huge haematoma of the posterior compartment of the thigh causing deformation and dysfunction of the limb
and resulting with acute haemorrhagic anaemia.
Conclusion. Our article is a contribution to the discussion on the need to pay attention to the possibility of haemorrhagic
complications in the course of anticoagulant treatment due to venous thrombosis in COVID-19 patients.
REFERENCES(20)
1.
Recommendations for the diagnosis and therapy of SARS-CoV-2 infections of the Polish Society of Epidemiologists and Infectiologists of November 12, 2021. Annex 1 to the recommendation of April 26, 2021. https://www.mp.pl/covid19/zale....
Levi M, Toh CH, Thachil J, et al. Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology. Br J Haematol. 2009; 145(1): 24–33. https://doi:10.1111/j.1365-214....
Lee Y, Jehangir Q, Li P, et al. Venous thromboembolism in COVID-19 patients and prediction model: a multicenter cohort study. BMC Infect Dis. 2022;22(1):462. https://doi:10.1186/s12879-022....
Llitjos JF, Leclerc M, Chochois C, et al. High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients. J Thromb Haemost. 2020;18(7):1743–1746. https://doi:10.1111/jth.14869.
Klok FA, Kruip MJHA, van der Meer NJM, et al. Incidence of thrombotic complications in critically ill ICU patients with COVID-19.” Thromb Res. 2020;191:145–147. https://doi:10.1016/j.thromres....
Li JY, Wang HF, Yin P, et al. Clinical characteristics and risk factors for symptomatic venous thromboembolism in hospitalized COVID-19 patients: a multicenter retrospective study. J Thromb Haemost. 2021;19(4):1.
Mahmoudabadi HZ, Hadadi A, Fattahi MR, et al. Rectus Sheath Haematoma in COVID-19 Patients as a Mortal Complication: A Retrospective Report. Int J Clin Pract. 2022;2022:7436827. https://doi: 10.1155/2022/7436827.
Nakamura H, Ouchi G, Miyagi K, et al. Case Report: Iliopsoas Haematoma during the Clinical Course of Severe COVID-19 in Two Male Patients. Am J Tropical Med Hyg. 2021;104(3):1018–1021. https://doi:10.4269/ajtmh.20-1....
Sabouri M, Rezvani M, Aminmansour B, et al. Spontaneous intramedullary haematoma in a patient with COVID-19 infection: A case report. Clin Case Rep. 2022;10(2):e05387. https://doi:10.1002/ccr3.5387.
Rogani S, Calsolaro V, Franchi R, et al. Spontaneous muscle haematoma in older patients with COVID-19: two case reports and literature review. BMC Geriatr. 2020;20(1):539. https://doi:10.1186/s12877-020....
Singh B, Mechineni A, Kaur P, et al. COVID-19 and bleeding at unusual locations: Report of four cases. Hematol Transfus Cell Ther. 2021; 43(2):214–218.
Patel I, Akoluk A, Douedi S, et al. Life-Threatening Psoas Haematoma due to Retroperitoneal Hemorrhage in a COVID-19 Patient on Enoxaparin Treated With Arterial Embolization: A Case Report. J Clin Med Res. 2020;12(7):458–461. https://doi:10.14740/jocmr4256.
Jiménez D, García-Sanchez A, Rali P, et al. Incidence of VTE and Bleeding Among Hospitalized Patients with Coronavirus Disease 2019: A Systematic Review and Meta-analysis. Chest. 2021;159(3):1182–1196.
Prince MR, Dev H, Lane EG, et al. Major hemorrhage and mortality in COVID-19 patients on therapeutic anticoagulation for venous thromboembolism. J Thromb Thrombolysis. 2022:1–7. https://doi:10.1007/s11239-022....
Abate V, Casoria A, Rendina D, et al. Spontaneous Muscle Haematoma in Patients with COVID-19: A Systematic Literature Review with Description of an Additional Case Series. Semin Thromb Hemost. 2022;48(1):100–108. https://doi:10.1055/s-0041-173....
Schulman S, Kearon C. Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. J Thromb Haemost. 2005;3(4):692-4. https://doi: 10.1111/j.1538-7836.2005.01204.x.
Godier A, Clausse D, Meslin S, et al. Major bleeding complications in critically ill patients with COVID-19 pneumonia. J Thromb Thrombolysis. 2021;52(1):18–21. https://doi:10.1007/s11239-021....
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.