Online first
Current issue
Archive
Special Issues
About the Journal
Publication Ethics
Anti-Plagiarism system
Instructions for Authors
Instructions for Reviewers
Editorial Board
Editorial Office
Contact
Reviewers
All Reviewers
2023
2022
2021
2020
2019
2018
2017
2016
General Data Protection Regulation (RODO)
Co-infection with Borrelia species and other tick-borne pathogens in humans: two cases from Poland.
1
Department of Parasitology, Institute of Zoology, University of Warsaw, Warsaw, Poland.
2
Institute of Medical Microbiology, Medical University Laboratories, Friedrich-Schiller-University Jena, Jena, Germany
3
Department of Parasitology, Institute of Zoology, University of Warsaw, Warsaw, Poland
Corresponding author
Edward Siński
Department of Parasitology, Insti- tute of Zoology, University of Warsaw, ul. Miecznikowa 1, 02-096 Warsaw, Poland
Department of Parasitology, Insti- tute of Zoology, University of Warsaw, ul. Miecznikowa 1, 02-096 Warsaw, Poland
Ann Agric Environ Med. 2010;17(2):309-313
KEYWORDS
ABSTRACT
Co-infection with Borrelia species and Anaplasma phagocytophilum or Babesia spp. was assessed in a retrospective study of tick-exposed individuals from southeastern Poland. The co-infection rate of these pathogens was found to be rather low (Borrelia spp./Anaplasma phagocytophilum--4.2%, 1/24; Borrelia spp./Babesia spp.--4.2%, 1/24). However, due to the increased prevalence of Borrelia spp. in Ixodes ricinus ticks in Poland and the recent emergence of new tick-borne infections, it is necessary to carefully evaluate the true risk of human infection with several pathogens using more sensitive and reliable diagnostic tools. This is the first report of human infection with Babesia spp. in Poland that has been confirmed by molecular techniques with homology of 98.9% to B. divergens or Babesia EU1.
REFERENCES (45)
1.
Adelson ME, Rao R-VS, Tilton RC, Cabets K, Eskow E, Fein L, Occi JL, Mordechai E: Prevalence of Borrelia burgdorferi, Bartonella spp., Babesia microti, and Anaplasma phagocytophila in Ixodes scapularis ticks collected in northern New Jersey. J Clin Microbiol 2004, 42, 2799-2801.
2.
Armstrong PM, Katavolos P, Caporale DA, Smith RP, Spielman A, Telford 3 rd SR: Diversity of Babesia infecting deer ticks (Ixodes dammini). Am J Trop Med Hyg 1998, 58, 739-742.
3.
Bakken JS, Dumler JS: Human granulocytic ehrlichiosis. Clin Infect Dis 2000, 31, 554-560.
4.
Belongia E: Epidemiology and impact of coinfections acquired from Ixodes ticks. Vector Borne Zoonotic Dis 2002, 2, 265-273.
5.
Bilski B: Occurrence of cases of borreliosis certified as an occupational disease in the province of Wielkopolska (Poland). Ann Agric Environ Med 2009, 16, 211-217.
6.
Buczek A, Rudek A, Bartosik K, Szymańska J, Wójcik-Fatla A: Seroepidemiological study of Lyme borreliosis among forestry workers in southern Poland. Ann Agric Environ Med 2009, 16, 257-261.
7.
Conrad PA, Kjemtrup AM, Carreno RA, Thomford J, Wainwright K, Eberhard M, Quick R, Telford 3rd SR, Herwaldt BL: Description of Babesia duncani n. sp. (Apicomplexa: Babesiidae) from humans and its differentiation from other piroplasms. Int J Parasitol 2006, 36, 779-789.
8.
de la Fuente J, Torina A, Naranjo V, Caracappa S, Di Marco V, Alongi A, Russo M, Maggio AR, Kocan KM: Infection with Anaplasma phagocytophilum in a seronegative patient in Sicily, Italy: case report. Ann Clin Microbiol Antimicrob 2005, 4, 15.
9.
Duh D, Petrovec M, Avsic-Zupanc T: Molecular characterization of human pathogen Babesia EU1 in Ixodes ricinus ticks from Slovenia. J Parasitol 2005, 91, 463-465.
10.
Fingerle V, Schulte-Spechtel UC, Ruzic-Sabljic E, Leonhard S, Hofmann H, Weber K, Pfister K, Strle F, Wilske B: Epidemiological aspects and molecular characterization of Borrelia burgdorferi s.l. from southern Germany with special respect to the new species Borrelia spielmanii sp. nov. Int J Med Microbiol 2008, 298, 279-290.
11.
Ginsberg HS: Potential effects of mixed infections in ticks on transmission dynamics of pathogens: comparative analysis of published records. Exp Appl Acarol 2008, 46, 29-41.
12.
Grzeszczuk A, Puzanowska B, Mięgoć H, Prokopowicz D: Incidence and prevalence of infection with Anaplasma phagocytophilum, prospective study in healthy individuals exposed to ticks. Ann Agric Environ Med 2004, 11, 155-157.
13.
Grzeszczuk A, Ziarko S, Kovalchuk O, Stańczak J: Etiology of tick-borne febrile illnesses in adult residents of North-Eastern Poland: report from a prospective clinical study. Int J Med Microbiol 2006, 296, 242-249.
14.
Halos L, Jamal T, Maillard R, Beugnet F, LeMenach A, Boulouis H-J, Vayssier-Taussat M: Evidence of Bartonella sp. in questing adult and nymphal Ixodes ricinus tick from France and co-infection with Borrelia burgdorferi sensu lato and Babesia sp. Vet Res 2005, 36, 79-87.
15.
Hartelt K, Oehme R, Frank H, Brockmann SO, Hassler, D, Kimmig P: Pathogens and symbionts in ticks: prevalence of Anaplasma phagocytophilum (Ehrlichia sp.), Wolbachia sp., Rickettsia sp., and Babesia sp. in southern Germany. Int J Med Microbiol 2004, 293 (suppl. 37), 86-92.
16.
Häselbarth K, Tenter AM, Brade V, Krieger G, Hunfeld KP: First case of human babesiosis in Germany – Clinical presentation and molecular characterization of the pathogen. Int J Med Microbiol 2007, 297, 197-204.
17.
Hermanowska-Szpakowicz T, Skotarczak B, Kondrusik M, Rymaszewska A, Sawczuk M, Maciejewska A, Adamska M, Pancewicz S, Zajkowska J: Detecting DNAs of Anaplasma phagocytophilum and Babesia in the blood of patients suspected of Lyme disease. Ann Agric Environ Med 2004, 11, 351-354.
18.
Herwaldt BL, Caccio S, Gherlinzoni F, Aspeck H, Slemenda SB, Piccaluga P, Martinelli G, Edelhofer R, Hollenstein, U, Poletti G, Pampiglione S, Loschenberger K, Tura S, Pieniazek NJ: Molecular characterization of a non-Babesia divergens organism causing zoonotic babesiosis in Europe. Emerg Infect Dis 2003, 9, 942-948.
19.
Hildebrandt A, Schmidt KH, Fingerle V, Wilske B, Straube E: Prevalence of granulocytic Ehrlichiae in Ixodes ricinus ticks in Middle Germany (Thuringia) detected by PCR and sequencing of a 16S ribosomal DNA fragment. FEMS Microbiol Lett 2002, 211, 225-230.
20.
Hildebrandt A, Hunfeld K-P, Baier M, Krumbholz A, Sachse S, Lorenzen T, Kiehntopf M, Fricke H-J, Straube E: First confirmed autochthonous case of human Babesia microti infection in Europe. Eur J Clin Microbiol Infect Dis 2007, 26, 595-601.
21.
Hildebrandt A, Tenter A, Strauber E, Hunfeld K-P: Human babesiosis in Germany: Just overlooked or truly new? Int J Med Microbiol 2008, 298 (suppl. 1), 336-346.
22.
Hodzic E, Fish D, Maretzki CM, De Silva AM, Feng S, Barthold SW: Acquisition and transmission of the agent of human granulocytic ehrlichiosis by Ixodes scapularis ticks. J Clin Microbiol 1998, 36, 3574-3578.
23.
Hunfeld KP, Brade V: Prevalence of antibodies against the human granulocytic ehrlichiosis agent in Lyme borreliosis patients from Germany. Eur J Clin Microbiol Infect Dis 1999, 18, 221-224.
24.
Hunfeld KP, BradeV: Zoonotic Babesia: possibly emerging pathogens to be considered for tick-infested humans in Central Europe. Int J Med Microbiol 2004, 293, 93-103.
25.
Kalinová Z, Halanová M, Čisláková L, Sulinová Z, Jarčuška P: Occurrence of IgG antibodies to Anaplasma phagocytophilum in humans suspected of Lyme borreliosis in eastern Slovakia. Ann Agric Environ Med 2009, 16, 285-288.
26.
Kjemtrup AM, Conrad PA: Human babesiosis: an emerging tickborne disease. Int J Parasitol 2000, 30, 1323-1337.
27.
Kondrusik M, Zajkowska J, Pancewicz SA, Grygorczuk S, Hermanowska-Szpakowicz T: Serological evidence of Borrelia burgdorferi and Anaplasma phagocytophilum infection among patients hospitalized with tick borne encephalitis (TBE). Int J Med Microbiol 2006, 296 (suppl.), 302-303.
28.
Milutinović M, Masuzawa T, Tomanović S, Radulović Z, Fukui T, Okamoto Y: Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum, Francisella tularensis and their co-infections in host-seeking Ixodes ricinus ticks collected in Serbia. Exp Appl Acarol 2008, 45, 171-183.
29.
Nieto NC, Foley JE: Meta-analysis of coinfection and coexposure with Borrelia burgdorferi and Anaplasma phagocytophilum in humans, domestic animals, wildlife, and Ixodes ricinus-complex ticks. Vector Borne Zoonotic Dis 2009, 9, 93-101.
30.
Petrovec M, Lotric FS, Zupanc TA, Strle F, Brouqui P, Roux V, Dumler JS: Human diseases in Europe caused by a granulocytic Ehrlichia species. J Clin Microbiol 1997, 35, 1556-1559.
31.
Piccolin G, Benedetti G, Doglioni C, Lorenzato C, Mancuso S, Papa N, Pitton L, Ramon MC, Zasio C, Bertiato G: A study of the presence of B. burgdorferi, Anaplasma (previously Ehrlichia) phagocytophilum, Rickettsia, and Babesia in Ixodes ricinus collected within the territory of Belluno, Italy. Vector Borne Zoonotic Dis 2006, 6, 24-31.
32.
Siński E, Pawełczyk A, Bajer A, Behnke JM: Abundance of wild rodents, ticks and environmental risk of Lyme borreliosis: a longitudinal study in an area of Mazury Lakes district of Poland. Ann Agric Environ Med 2006, 13, 295-300.
33.
Siński E, Bajer A, Welc R, Pawełczyk A, Ogrzewalska M, Behnke JM: Babesia microti: Prevalence in wild rodents and Ixodes ricinus ticks from the Mazury Lakes District of north-eastern Poland. Int J Med Microbiol 2006, 296 s1, 137-143.
34.
Skotarczak B, Wodecka B, Cichocka A: Coexistance DNA of Borrelia burgdorferi sensu lato and Babesia microti in Ixodes ricinus ticks from north-western Poland. Ann Agric Environ Med 2002, 9, 25-28.
35.
Skotarczak B, Rymaszewska A, Wodecka B, Sawczuk M: Molecular evidence of coinfection of Borrelia burgdorferi sensu lato, human granulocytic ehrlichiosis agent, and Babesia microti in ticks from northwestern Poland. J Parasitol 2003, 89, 194-196.
36.
Stańczak J, Gabre RM, Kruminis-Łozowska W, Racewicz M, Kubica-Bienat B: Ixodes ricinus as a vector of Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia microti in urban and suburban forests. Ann Agric Environ Med 2004, 11, 109-114.
37.
Steere AC, McHugh G, Suarez C, Hoitt J, Damle N, Sikand VK: Prospective study of coinfection in patients with erythema migrans. Clin Infect Dis 2003, 36, 1078-1081.
38.
Steiner FE, Pinger RR, Vann CN, Grindle N, Civitello D, Clay K, Fuqua C: Infection and co-infection rates of Anaplasma phagocytophilum variants, Babesia spp., Borrelia burgdorferi, and the rickettsial endosymbiont in Ixodes scapularis (Acari: Ixodae) from sites in Indiana, Maine, Pennsylvania, and Wisconsin. J Med Entomol 2008, 45, 289-297.
39.
Swanson SJ, Neitzel D, Reed KD, Belongia EA: Coinfections acquired from ixodes ticks. Clin Microbiol Rev 2006, 19, 708-727.
40.
Tylewska-Wierzbanowska S, Chmielewski T, Kondrusik M, Hermanowska-Szpakowicz T, Warsaw W, Sulek K: First cases of acute human granulocytic ehrlichiosis in Poland. Eur J Clin Microbiol Infect Dis 2001, 20, 196-198.
41.
Vorou RM, Papavassiliou VG, Tsiodras S: Emerging zoonoses and vector-borne infections affecting humans in Europe. Epidemiol Infect 2007, 135, 1231-1247.
42.
Welc-Falęciak R: Rodent blood parasites Babesia microti and Bartonella spp. pathogenic in humans: environmental and molecular studies. PhD thesis, Faculty of Biology, University of Warsaw, 2009.
43.
Wielinga P, Fonville M, Sprong H, Gaasenbeek C, Borgsteede F, van der Giessen JWB: Persistent detection of Babesia EU1 and Babesia microti in Ixodes ricinus in the Netherlands during a 5-year surveillance: 2003-2007. Vector Borne Zoonotic Dis 2009, 9, 119-121.
44.
Woessner R, Gaertner BC, Grauer MT, Weber K, Mueller-Lantzsch N, Hunfeld KP, Treib J: Incidence and prevalence of infection with human granulocytic ehrlichiosis agent in Germany. A prospective study in young healthy subjects. Infection 2001, 29, 271-273.
45.
Wójcik-Fatla A, Szymańska J, Wdowiak L, Buczek A, Dutkiewicz J: Coincidence of three pathogens (Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia microti) in Ixodes ricinus ticks in the Lublin macroregion. Ann Agric Environ Med 2009, 16, 151-158.
Share
RELATED ARTICLE
| eISSN: | 1898-2263 |
| ISSN: | 1232-1966 |
Improvement of visual identification of the journal - task financed under the agreement No. 618/P-DUN/2019 by the Minister of Science and Higher Education allocated to the activities of disseminating science.
Generation of the DOI (Digital Object Identifier) - task financed under the agreement No. 618/P-DUN/2019 by the Minister of Science and Higher
© 2006-2024 Journal hosting platform by Bentus
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
