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CASE REPORT
An epileptic seizure and haemorrhage into the ventricular system of the brain as the first
manifestations of acquired haemophilia A – Case report
1
Department of Haematooncology and Bone Marrow Transplantation, Medical University, Lublin, Poland
2
Department of Neurosurgery and Pediatric Neurosurgery, Medical University, Lublin, Poland
Corresponding author
Adrian Juda
Department of Haematooncology and Bone Marrow Transplantation, Medical University in Lublin, Aleje Racławickie 1, 20-059, Lublin, Poland
Department of Haematooncology and Bone Marrow Transplantation, Medical University in Lublin, Aleje Racławickie 1, 20-059, Lublin, Poland
Ann Agric Environ Med. 2021;28(3):531-533
KEYWORDS
TOPICS
ABSTRACT
Acquired haemophilia (AH) is a suddenly occurring severe blood diathesis that affects both males and females and is caused by autoantibodies which inhibit coagulation factor VIII. The report describes an unusual case of acquired haemophilia in which an epileptic seizure and haemorrhage into the ventricular system of the brain were the first manifestations of the disease. In addition, APTT was prolonged to 94.6 seconds and the factor VIII level was as low as 1.5%. The level of anti-FVIII antibody was extremely high – 272BU/ml. The patient did not undergo invasive diagnostic procedure or an operation. Recombinant factor VIIa was used to control the bleeding. In order to eradicate the inhibitor, the patient received prednisone and cyclophosphamide. Complete remission was achieved after 5.5 weeks of treatment.
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| eISSN: | 1898-2263 |
| ISSN: | 1232-1966 |
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