Allergy to tetramethylthiuram disulphide, a component of pesticides and rubber.

E E Rudzki 1, P P Rebandel 2
1 - Department of Dermatology, Medical Academy, Warsaw, Poland
2 -
Ann Agric Environ Med
1998; 5 (1):
ICID: 4639
Article type: Original article
 
 
Since 1970 patch tests have been carried out on 39,420 consecutive patients with contact dermatitis using two rubber accelerators: dimercaptobenzothiazole (2-MBT) and tetramethylthiuram disulphide (TMTD). The second substance is also a component of pesticides. Over the years, the incidence of sensitivity to these substances was similar. But in the recent years the incidence of TMTD sensitivity began rising. This fact is explained by more frequent use of rubber gloves connected with AIDS prophylaxis. Independently of this, it was found that a part of alcoholic patients treated with disulfiram (tetraethylthiuram disulphide) showed a cross-reaction to TMTD.
PMID 9852489 - click here to show this article in PubMed
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