A continuous 2-year volumetric aerobiological survey was conducted in Berhamporetown, a centrally located and representative part of West Bengal, India. The aim of the study was toassess the allergising potential of airborne pollen grains of West Bengal. A total of 31 pollen typeswere identified of which Poaceae (grasses) pollen showed maximum frequency, followed by Cyperaceae, Cassiasp., Acacia auriculiformis, etc. The seasonal periodicities of the pollen types and their relationshipto meteorological conditions were investigated. It was found that the pollen concentration is positivelycorrelated with temperature and negatively correlated with rainfall and relative humidity. Clinical investigationsby skin prick test were carried out to detect allergenicity of pollen types. Eighteen common airbornepollen types induced positive responses of which pollen extracts of Saccharum officinarum (grass), Azadirachtaindica, Cocos nucifera, Phoenix sylvestris, Cyperus rotundus and Eucalyptus citriodora showed strongestsensitising potential. This result is consistent with previous investigations in different parts of WestBengal.