Neighbours of intensive livestock production facilities frequently complainof odour annoyance. They are also concerned about potential negative health effects of environmentalexposures to livestock emissions. Quality of life (QoL) was assessed in residents of a rural communityneighbouring an area with high concentration of animal farms. A postal cross-sectional survey was carriedout among the 4,537 residents, aged 18-44 years. Of these, 3,112 (69 %) responded to questions on annoyanceby livestock odours (4-point scale), on QoL (assessed by the short form 12, SF-12), and on potentialconfounders (age, gender, respiratory symptoms, smoking, living on or close to a farm, and employmentstatus). SF-12 scores were available for 2745 (88 %) subjects. Sixty-one percent of the respondents complainedabout unpleasant odours, 91 % of these accused livestock as source of these odours. Physical and emotionalSF-12 scores were inversely related to annoyance scores. Better risk communication might improve QoLin concerned neighbours of intensive livestock production facilities.