Beta(1-->3)-glucan exposure levels among workers in four British Columbia sawmills.

Lisa A. Ronald 1, Hugh W. Davies 2, Karen H. Bartlett 2, Susan M. Kennedy 2, Kay Teschke 2, Jacques Spithoven 2, Martine Dennekamp 2, Paul A. Demers 2
1 - School of Occupational and Environmental Hygiene, University of British Columbia, Vancouver, BC, Canada
2 -
Ann Agric Environ Med
2003; 10 (1):
ICID: 13816
Article type: Original article
 
  Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC, Canada
School of Occupational and Environmental Hygiene, University of British Columbia, Vancouver, BC, Canada
School of Occupational and Environmental Hygiene, University of British Columbia, Vancouver, BC, Canada,
Institute for Risk Assessment Sciences, Utrecht University, The Netherlands
School of Occupational and Environmental Hygiene, University of British Columbia, Vancouver, BC, Canada,

Beta(1-->3)-glucans were extracted from wood dust samples taken during the summer of 1997 at four British Columbia sawmills. Personal dust samples were collected using a GSP-sampler for inhalable dust and the sampling strategy targeted all production and maintenance jobs at least once at each mill. Potential exposure determinants data were documented concurrently, including weather conditions, log storage methods, wood conditions, species, production level, jobs and tasks. beta(1-->3)-glucans were measured by enzyme inhibition immunoassay (EIA). A total of 223 personal beta(1-->3)-glucan samples were analyzed. 45.7% were below the limit of detection (LOD). Geometric mean concentration ranged from 3.5 to 18.9 micro g/m(3) across the four mills. The highest levels were measured at the Interior mills, particularly in the log processing and sawmill areas. Multivariate regression models indicated that land-based log storage, clean-up jobs, high wood dust concentration, lumber yard department and the interaction between land-based log storage method and log processing department were associated with increased beta(1-->3)-glucan concentration.
PMID 12852730 - click here to show this article in PubMed
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