Association of anthropometric measures of obesity and chronic kidney disease in elderly women

Andrzej Jaroszynski 1, Tadeusz Dereziński  2, Anna Jaroszyńska  3, Tomasz Zapolski  3, Beata Wąsikowska 2, Andrzej Wysokiński  3, Arkadiusz Jawień  4, Wojciech Załuska  5, Andrzej Horoch  6
1 - Department of Family Medicine, Medical University of Lublin, Poland
2 - Out-Patient Clinic Esculap Gniewkowo,Gniewkowo, Poland
3 - Department of Cardiology, Medical University of Lublin, Poland
4 - Department of Vascular Surgary and Angiology Nicolaus Copernicus University, Bydgoszcz, Poland
5 - Department of Nephrology, Medical University of Lublin, Poland
6 - Institute of Rural Health, Lublin, Poland
Ann Agric Environ Med
2016; 23 (4):
ICID: 1226859
Article type: Original article
 
 
Introduction and objective. Growing evidence suggests that obesity is an important contributor to the development of chronic kidney disease (CKD). The relationship between obesity and CKD is complex and not completely understood, and the best anthropometric index of obesity in predicting CKD is controversial. This study aimed to determine the best anthropometric index of obesity in predicting CKD in a population of elderly women.
Materials and methods. Anthropometric indexes of obesity including body mass index (BMI), waist circumference (WC), waist-to-height ratio (WheiR) and waist-to-hip-ratio (WHR), were obtained in 730 selected females. Biochemical measurements including blood glucose, lipid profile, and 2-h postprandial blood glucose were performed. GFR was estimated by using CKD-EPI equation.
Results. The prevalence of CKD stage ≥ 3 was 12.2%. Overweight and obesity was found in 50% and 36% of participants, respectively. Increased central fat distribution, as defined by WheiR, WC and WHR, was found in 89.6%, 91.7% and 89.4% individuals, respectively. Univariate linear regression analysis showed positive correlations between CKD and age (p<0.001), BMI (p<0.001), WC (p<0.001), WHR (p=0.007), WheiR (p<0.001), diabetes (p=0.002), as well as triglicerydes (p=0.031), and negative correlation between CKD and HDL level (p=0.017). Multivariable analysis demonstrated that hypertension, diabetes, WC and WheiR were independent predictors of CKD. The area under the receiver operating characteristics curve was best for WheiR (0.647), followed by WC (0.620), BMI (0.616), and WHR (0.532).
Conclusions. Abdominal obesity is an important predictor of CKD. Of commonly used anthropometric parameters of obesity WheiR ≥ 0.6 is particularly associated with CKD in elderly females.
DOI: 10.5604/12321966.1226859
PMID 28030936 - click here to show this article in PubMed
  FULL TEXT STATS

Recommend this article to:

Name:
E-mail:
From:
Language:


Related articles in IndexCopernicus™
     anthropometric [2 related records]
     waist circumference; [1 related records]
     body mass index [21 related records]
     waist-to-hip ratio [6 related records]
     Waist-to-Height Ratio [5 related records]
     chronic kidney disease [9 related records]
     obesity [46 related records]



 

Related articles

M Bahadori, L Kohan,
ASSOCIATION Of ASSESSMENT BETWEEN VAL109ASP OMENTI...
Background: obesity is the major health problems affecting communities worldwide and the prevalence is rapidly rising. Obesity as a lifestyle-related factor increases the risk of many diseases. Omentin is a new adipocytokine that is abundantly expres...
ABSTRACT
M Hemberal, V Chandregowda,
Evaluation of waist-to-hip ratio as a predictor of...
Background: Abdominal obesity judged by increased waist-to-hip ratio (WHR) is an important risk factor for atheroscle - rosis. One of the mechanisms postulated by which truncal obesity increases coronary risk is high blood pressure (BP). It is ...
ABSTRACT
S Garshasbi, D Salimi,
Investigation of the molecular relationship betwee...
Background: Cancer and obesity are two major public health concerns. More than 12 million cases of cancer are reported annually. Many reports confirmed obesity as a risk factor for cancer. The molecular relationship between obesity and breast cancer ...
ABSTRACT