Acrylamide content in cigarette mainstream smoke and estimation of exposure to acrylamide from tobacco smoke in Poland

Hanna Mojska 1, Iwona Gielecińska 1, Andrzej Cendrowski 2
1 - Department of Metabolomics, National Food and Nutrition Institute, Warsaw, Poland
2 - Division of Fruit and Vegetable Technology, Department of Food Technology, Faculty of Food Sciences, Warsaw University of Life Sciences (SGGW)
Ann Agric Environ Med
2016; 23 (3):
ICID: 1219187
Article type: Original article
Introduction and objective. Acrylamide is a “probably human carcinogen” monomer that can form in heated starchy food as a result of a reaction between asparagine and reducing sugars via Maillard reaction. The main source of acrylamide in human diet are potato products, cereal products and coffee. Tobacco smoke may be another significant source of exposure to acrylamide. The aim of our study was to determine acrylamide content in cigarettes available on the Polish market and to estimate the exposure to acrylamide originating from tobacco smoke in smokers in Poland.
Materials and methods. The material was cigarettes of the top five brands bought in Poland and tobacco from non-smoked cigarettes. Acrylamide content in cigarettes mainstream smoke was determined by LC-MS/MS. Exposure assessment was carried out using analytical data of acrylamide content in cigarettes and the mean quantity of cigarettes smoked daily by smokers in Poland, assuming body weight at 70 kg.
Results. The mean content of acrylamide was 679.3 ng/cigarette (range: 455.0 – 822.5 ng/cigarette). The content of acrylamide was evidenced to correlate positively with total particulate matter (TPM) content in cigarettes. The estimated average exposure to acrylamide from tobacco smoke in adult smokers in Poland is 0.17 μg/kg b.w./day.
Conclusions. Our results demonstrate that tobacco smoke is a significant source of acrylamide and total exposure to acrylamide in the population of smokers, on average, is higher by more than 50% in comparison with non-smokers. Our estimation of exposure to acrylamide from tobacco smoke is the first estimation taking into account the actual determined acrylamide content in the cigarettes available on the market.

DOI: 10.5604/12321966.1219187
PMID 27660868 - click here to show this article in PubMed

Recommend this article to:


Related articles in IndexCopernicus™
     exposure assessment [23 related records]
     LC-MS/MS [45 related records]
     cigarette mainstream smoke [0 related records]
     Acrylamide [31 related records]


Related articles

A Jeżewska,
Akrylamid. Oznaczanie w powietrzu na stanowiskach ...
Akrylamid jest bezwonnym, białym i krystalicznym ciałem stałym, dobrze rozpuszczalnym w rozpuszczalnikach polarnych (woda, etanol). Jest to substancja syntetyczna stosowana w wielu dziedzinach przemysłu, głównie do produkcji poliakrylamidu. M...
A Modenese, F Bisegna,
Outdoor work and solar radiation exposure: Evaluat...
Background: The health risk related to an excessive exposure to solar radiation (SR) is well known. The Sun represents the main exposure source for all the frequency bands of optical radiation, that is the part of the electromagnetic spectrum ranging...
S Li-li, M Fan-hua,
目的 建立测定大鼠血浆中黄体酮的液相色谱?鄄串联质谱(LC-MS/MS)法。方法 血浆样品采用液-液萃取法,经正己烷?鄄二氯甲烷-异丙醇(100∶50∶5, V/V/V)提取后,以甲醇-水(75∶25, V/V...