Relationship between concentrations of microbiological agents in the air of agricultural settings and occurrence of work-related symptoms in exposed persons

Barbara Mackiewicz 1, Czesława Skórska 2, Jacek Dutkiewicz 2
1 - Department of Pneumonology, Oncology and Allergology, Medical University of Lublin, Lublin, Poland
2 - Department of Biological Health Hazards and Parasitology, Institute of Rural Health, Lublin, Poland
Ann Agric Environ Med
2015; 22 (3):
ICID: 1167717
Article type: Review article
For assessment of the dose-response relationship between concentrations of microbial agents in the air of various agricultural settings and occurrence of work-related symptoms in exposed workers, a meta-analysis of the results obtained in 1994–2007 on the territory of eastern Poland was performed. The studies on the airborne concentrations of total culturable microorganisms, mesophilic bacteria, Gram-negative bacteria, thermophilic actinomycetes, fungi, and bacterial endotoxins, as well as on the frequency of work-related respiratory and general symptoms in the exposed workers, were carried out at grain, thyme, valerian, flax, and hop handling on farms, in cow barns, piggeries, horse stables and in a modern hatchery. The airborne concentrations of the total microorganisms were in the range of 9.2–1236.5 × 103 CFU/m3 , of the total mesophilic bacteria 3.5–1225.8 × 103 CFU/m3 , of Gram-negative bacteria 0.0- 46.2 × 103 CFU/m3 , of thermophilic actinomycetes 0.0–7.1 × 103 CFU/m3 , of fungi 2.1–77.9 × 103 CFU/m3 , and of bacterial endotoxin 0.00925–429.55 µg/m3 . The frequency of work-related symptoms ranged between 21.7–63.8%. In a meta-analysis for assessment of the correlations between the log-transformed concentrations of airborne microbial agents and the occurrence of work-related symptoms, the multiple regression test was applied. Statistically significant correlations were found between the occurrence of work-related symptoms and the concentration of total airborne microorganisms (R=0.748555; P=0.020317), mesophilic bacteria (R=0.7573; P=0.029548), Gram-negative bacteria (R=0.835938; P=0.019129), and endotoxins (R=0.705356; P=0.03378). The correlations between the concentrations of thermophilic actinomycetes and fungi, on one side, and frequency of work-related symptoms on the other, did not attain the threshold of significance (P=0.087049 and P=0.062963, respectively). Results of the meta-analysis confirm harmful health effects of the total airborne microorganisms, total airborne mesophilic bacteria, airborne Gram-negative bacteria, and airborne bacterial endotoxin on the occupationally-exposed agricultural workers, and indicate a need for the establishment of internationally recognized occupational exposure limits for these microbial agents.
DOI: 10.5604/12321966.1167717
PMID 26403118 - click here to show this article in PubMed

Recommend this article to:


Related articles in IndexCopernicus™
     air of agricultural settings [0 related records]
     exposed persons [0 related records]
     microbiological agents [1 related records]


Related articles

M Mączewski, M Duda,
The effect of omega-3 polyunsaturated fatty acids ...
Introduction. Omega-3 polyunsaturated fatty acids (ω-3 PUFA) are essential fatty acids that cannot be synthesized by mammals and must be delivered with food. Epidemiological observations suggest that supplementation of ω-3 PUFA reduces cardiovascul...
K Stojecki, J Sroka,
Epidemiological survey in Łęczyńsko-Włodawski...
Faecal samples from 297 farm animals were collected from 18 households in distinct sites of the Łęczyńsko-Włodawskie Lake District of eastern Poland. They included samples from 86 cattle (Bos taurus), 84 pigs (Sus scrofa f. domestica[/i...
J Dutkiewicz, B Mackiewicz,
Pantoea agglomerans: a mysterious bacterium of evi...
Pantoea agglomerans, a gammaproteobacterium of plant origin, possesses many beneficial traits that could be used for the prevention and/or treatment of human and animal diseases, combating plant pathogens, promotion of plant growth and ...