Impact of heavy metals on the female reproductive system

Piotr Rzymski 1, Katarzyna Tomczyk 2, Pawel Rzymski 2, Barbara Poniedziałek 1, Tomasz Opala 2, Maciej Wilczak 3
1 - Department of Biology and Environmental Protection, Poznan University of Medical Sciences, Poznan, Poland
2 - Department of Mother’s and Child’s Health, Poznan University of Medical Sciences, Poznan, Poland
3 - Department of Educational Medicine, Poznan University of Medical Sciences, Poznan, Poland
Ann Agric Environ Med
2015; 22 (2):
ICID: 1152077
Article type: Review article
 
 
Introduction. It has been recognized that environmental pollution can affect the quality of health of the human population. Heavy metals are among the group of highly emitted contaminants and their adverse effect of living organisms has been widely studied in recent decades. Lifestyle and quality of the ambient environment are among these factors which can mainly contribute to the heavy metals exposure in humans.
Objective. A review of literature linking heavy metals and the female reproductive system and description of the possible associations with emission and exposure of heavy metals and impairments of female reproductive system according to current knowledge.
Results. The potential health disorders caused by chronic or acute heavy metals toxicity include immunodeficiency, osteoporosis, neurodegeneration and organ failures. Potential linkages of heavy metals concentration found in different human organs and blood with oestrogen-dependent diseases such as breast cancer, endometrial cancer, endometriosis and spontaneous abortions, as well as pre-term deliveries, stillbirths and hypotrophy, have also been reported.
Conclusions. Environmental deterioration can lead to the elevated risk of human exposure to heavy metals, and consequently, health implications including disturbances in reproduction. It is therefore important to continue the investigations on metal-induced mechanisms of fertility impairment on the genetic, epigenetic and biochemical level.

DOI: 10.5604/12321966.1152077
PMID 26094520 - click here to show this article in PubMed
  FULL TEXT STATS

Recommend this article to:

Name:
E-mail:
From:
Language:


Related articles in IndexCopernicus™
     Mercury [103 related records]
     Lead [259 related records]
     Cadmium [217 related records]
     Female reproductive system [2 related records]
     heavy metals [520 related records]



 

Related articles

H Dimitrov, V Mitkovska,
Bioaccumulation of Cadmium and Lead in Rodent Spec...
The levels of the toxic metals, Cd and Pb, were measured in liver of yellow-necked mouse (Apodemus flavicollis Melchior, 1834), Mediterranean mouse (Mus macedonicus Petrov & Ružić, 1983) and common vole (Microtus arvalis Pallas, 1778) from the ...
ABSTRACT
J Pečkytė, E Baltrėnaitė,
Assessment of heavy metals leaching from (bio)char...
Biochar can be produced from many various feedstock including biomass residues such as straw, branches, sawdust and other agricultural and forestry waste. One of the alternatives is to obtain biochar from industrial sewage sludge, however, the use of...
ABSTRACT
S Kozub,
Анализ современного состоя...
Рассмотрены основные источники сырья и конечные продукты, содержащие кадмий. Проанализированы их характеристики, возможности использо...
ABSTRACT