Airway inflammation among compost workers exposed to actinomycetes spores

Kari Kulvik Heldal 1, Lene Madsø 1, Wijnand Eduard 1
1 - National Institute of Occupational Health, Oslo, Norway
Ann Agric Environ Med
2015; 22 (2):
ICID: 1152076
Article type: Original article
Objectives. To study the associations between exposure to bioaerosols and work-related symptoms, lung function and biomarkers of airway inflammation in compost workers.
Materials and method. Personal full-shift exposure measurements were performed on 47 workers employed at five windrow plants (n=20) and five reactor plants (n=27). Samples were analyzed for endotoxins, bacteria, fungal and actinomycetes spores. Health examinations were performed on workers and 37 controls before and after work on the day exposure was measured. The examinations included symptoms recorded by questionnaire, lung function by spirometry and nasal dimensions by acoustic rhinometry (AR). The pneumoproteins CC16, SP-D and SP-A were measured in a blood sample drawn at the end of the day.
Results. The levels of endotoxins (median 3 EU/m3 , range 0–730 EU/m3 ) and actinomycetes spores (median 0.2 × 106 spores/m3 , range 0–590 × 106 spores/m3 ) were significantly higher in reactor plants compared to windrow plants. However, windrow composting workers reported more symptoms than reactor composting workers, probably due to use of respiratory protection. Exposure-response relationships between actinomycetes spores exposure and respiratory effects, found as cough and nose irritation during a shift, was significantly increased (OR 4.3, 95% CI 1.1–16, OR 6.1, 95% CI 1.5–25, respectively, p<0.05) among workers exposed to 0.02–0.3 × 106 actinomycetes spores/m 3 , and FEV1/FVC% decreased cross shift (b=–3.2, SE=1.5%, p<0.01). Effects were weaker in the highest exposed group, but these workers used respiratory protection, frequently limiting their actual exposure. No relationships were found between exposure and pneumoprotein concentrations.
Conclusions. The major agent in the aerosol generated at compost plants was actinomycetes spores which was associated with work related cough symptoms and work-shift lung function decrease.

DOI: 10.5604/12321966.1152076
PMID 26094519 - click here to show this article in PubMed

Recommend this article to:


Related articles in IndexCopernicus™
     composting [24 related records]
     pneumoproteins [0 related records]
     actinomycetes spores [0 related records]
     Exposure [77 related records]


Related articles

, ,
The Service Learning (Outreach) at Loyola College, Chennai is an eye-opener for the students to find many harsh realities which still exist in Indian society. It really motivates students to be human. Exposure to the urban realities in the slums of ...
C Ghinea, M Gavrilescu,
Costs analysis of municipal solid waste management...
Effective management of solid waste has become environmentally and economically mandatory due to the increase of environmental problems. In this context, the evaluation of economic aspects is imperative since the implementation of a solid waste manag...
, ,
 Technology for Rapid Composting of Cotton St...
 An experiment was under taken for rapid composting of cotton stalks at Main Dry Farming Research Station, Junagadh Agricultural University, Targhadia (Rajkot) during 2009. There were seven treatments: T1: cotton stalk only (control), T2: cott...