Airway inflammation among compost workers exposed to actinomycetes spores

Kari Kulvik Heldal 1, Lene Madsø 1, Wijnand Eduard 1
1 - National Institute of Occupational Health, Oslo, Norway
Ann Agric Environ Med
2015; 22 (2):
ICID: 1152076
Article type: Original article
 
 
Objectives. To study the associations between exposure to bioaerosols and work-related symptoms, lung function and biomarkers of airway inflammation in compost workers.
Materials and method. Personal full-shift exposure measurements were performed on 47 workers employed at five windrow plants (n=20) and five reactor plants (n=27). Samples were analyzed for endotoxins, bacteria, fungal and actinomycetes spores. Health examinations were performed on workers and 37 controls before and after work on the day exposure was measured. The examinations included symptoms recorded by questionnaire, lung function by spirometry and nasal dimensions by acoustic rhinometry (AR). The pneumoproteins CC16, SP-D and SP-A were measured in a blood sample drawn at the end of the day.
Results. The levels of endotoxins (median 3 EU/m3 , range 0–730 EU/m3 ) and actinomycetes spores (median 0.2 × 106 spores/m3 , range 0–590 × 106 spores/m3 ) were significantly higher in reactor plants compared to windrow plants. However, windrow composting workers reported more symptoms than reactor composting workers, probably due to use of respiratory protection. Exposure-response relationships between actinomycetes spores exposure and respiratory effects, found as cough and nose irritation during a shift, was significantly increased (OR 4.3, 95% CI 1.1–16, OR 6.1, 95% CI 1.5–25, respectively, p<0.05) among workers exposed to 0.02–0.3 × 106 actinomycetes spores/m 3 , and FEV1/FVC% decreased cross shift (b=–3.2, SE=1.5%, p<0.01). Effects were weaker in the highest exposed group, but these workers used respiratory protection, frequently limiting their actual exposure. No relationships were found between exposure and pneumoprotein concentrations.
Conclusions. The major agent in the aerosol generated at compost plants was actinomycetes spores which was associated with work related cough symptoms and work-shift lung function decrease.

DOI: 10.5604/12321966.1152076
PMID 26094519 - click here to show this article in PubMed
  FULL TEXT STATS

Recommend this article to:

Name:
E-mail:
From:
Language:


Related articles in IndexCopernicus™
     composting [24 related records]
     pneumoproteins [0 related records]
     actinomycetes spores [0 related records]
     Exposure [77 related records]



 

Related articles

C Ekpenyong, A Asuquo,
Recent advances in occupational and environmental ...
The impact of health and environmental hazards, associated with the constituents of gasoline, on occupationally exposed workers has been recorded over the past few decades. However, the scientific literature on their pathogenic potential remains inco...
ABSTRACT

Rozprzestrzenianie się w powietrzu nanoobiektów ...
Wstęp: W wyniku włączenia w pomieszczeniu kuchenki mikrofalowej w powietrzu są wytwarzane cząstki o nanowymiarach. Wytwarzane cząstki mogą się rozprzestrzeniać w powietrzu w pomieszczeniu. Materiał i metody: Badanie rozprzestrzeniania się ...
ABSTRACT

Air pollution and emergency department visits for ...
Objectives: The purpose of this study was to examine the associations between emergency department (ED) visits for conjunctivitis and ambient air pollution levels in urban regions across the province of Ontario, Canada. Material and Methods: Informat...
ABSTRACT