One-step synthesis of highly-biocompatible spherical gold nanoparticles using Artocarpus heterophyllus Lam. (jackfruit) fruit extract and its effect on pathogens

Nagaraj Basavegowda 1, Gowri Dhanya Kumar  1, Bozena Tyliszczak 2, Zbigniew Wzorek 3, Agnieszka Sobczak-Kupiec 4
1 - Department of Biotechnology, Shridevi Institute of Engineering & Technology, Tumkur, Karnataka, India
2 - Department of Chemistry and Technology of Polymers, Cracow University of Technology, Cracow, Poland
3 - Institute of Inorganic Chemistry and Technology, Cracow University of Technology, Cracow, Poland
4 - Institute of Inorganic Chemistry and Technology, Cracow University of Technology, Cracow, Poland
Ann Agric Environ Med
2015; 22 (1):
ICID: 1141374
Article type: Original article
 
 
Introduction. Novel approaches for the synthesis of gold nanoparticles (AuNPs) are of great importance due to its vast spectrum of applications in diverse fields, including medical diagnostics and therapeutics. Te presented study reports the successful AuNPs’ synthesis using Artocarpus heterophyllus Lam. extract, and provides detailed characterization and evaluation of its antibacterial potential.
Objective. The aim was to develop a cost-effective and environmentally friendly synthesis method of gold nanoparticles using aqueous fruit extract of Artocarpus heterophyllus Lam. as a reducing and capping agent, which has proven activity against human pathogens, such as microbial species E.coli and Streptobacillus sps.
Materials and method. Characterizations were carried out using ultraviolet-visible (UV-Vis) spectrophotometry, scanning electron microscopy (SEM), energy dispersive X-ray and Fourier-Transform infra-red spectroscopy (FT-IR).
Results. SEM images showed the formation of gold nanoparticles with an average size of 20–25 nm. Spectra collected while infra-red analysis contained broad peaks in ranges from 4000–400 cm -1 .
Conclusions. It can be concluded that the fruit of Artocarpus heterophyllus Lam. can be good source for synthesis of gold nanoparticles which showed antimicrobial activity against investigated microbes, in particul E. coli, and Streptobacillus. An important outcome of this study will be the development of value-added products from the medicinal plant Artocarpus heterophyllus Lam. for the biomedical and nanotechnology-based industries.

DOI: 10.5604/12321966.1141374
PMID 25780834 - click here to show this article in PubMed
  FULL TEXT STATS

Recommend this article to:

Name:
E-mail:
From:
Language:


Related articles in IndexCopernicus™
     EDX analysis [2 related records]
     X-ray spectroscopy [0 related records]
     UV- visible spectra [0 related records]
     Artocarpus heterophyllus [0 related records]



 

Related articles

M Pawlita-Posmyk, M Wzorek,
 Analysis of domestic sewage treatment system...
There is a growing interest in household sewage treatment systems with increasing popularity of such solutions. Household sewage treatment systems are constantly improved and developed in order to effectively increase efficiency of wastewater tre...
ABSTRACT
M Wzorek, A Król,
Zagrożenia wynikające z magazynowania paliw z od...
Magazynowanie paliw prowadzone na otwartej przestrzeni stwarza warunki do niekorzystnego oddziaływania czynników atmosferycznych na jakość paliw i może również prowadzić do wymywania składników, często szkodliwych dla środowiska. W artyku...
ABSTRACT
A Jaroń, A Kuc,
Smectite sorbents designed for the removal of H[su...
Multilayered clay minerals have been widely studied as potential sorbents for the absorption of various gases including the aggressive ones that cause corrosion. In the present work smectite 2:1 (Krzeniów deposits) has been used as the base material...
ABSTRACT