Level of magnesium in patients with depression treated with lithium – pilotage research

Marta Makara-Studzińska 1, Wojciech Dąbrowski 2, Małgorzata Kiełczykowska 3, Irena Musik 3
1 - Independent Psychic Health Unit, Medical University, Lublin, Poland
2 - Department of Anaesthesiology and Intensive Therapy, Medical University, Lublin, Poland
3 - Chair and Department of Medical Chemistry, Medical University, Lublin, Poland
Ann Agric Environ Med
2013; 20 (1):
ICID: 1041684
Article type: Original article
 
 
Introduction. Depression is a major public health problem. Magnesium (Mg2+) is involved in many metabolic processes as an activator of over 300 different enzymes. For the last 60 years lithium (Li+) compounds have been used in psychiatry. Li+ salts are regarded as the first choice medicine in the treatment of affective disorders and are also applied as an adjuvant intensifying the therapy in drug-resistant depression patients.
Objective. The objective of the study was an analysis of the relationship between the levels of magnesium, lithium, and education and place of residence of patients hospitalized due to depression.
Material and methods. Patients with bipolar affective disorders undergoing lithium therapy during their stay in the Department of Psychiatry at the Medical University in Lublin were examined. Patients were divided into three groups according to education level and were also analyzed according to place of residence.
Results. In the group of patients in the study, a significantly lower level of magnesium was found (p=0.02) in blood plasma of patients with secondary education level, compared to those who had elementary education. There was also a significantly higher level of magnesium (p=0.01) in blood plasma of patients who lived in urban areas, compared to rural inhabitants. No statistically significant differences were noted between lithium level in plasma, and the patients’ place of residence (p=0.34).
Conclusion. Significantly higher plasma magnesium levels were observed among city than village inhabitants, there was also a relationship between type of education and magnesium level in blood plasma of the patients in the study. Further studies including larger groups of patients should be performed to enable a final conclusion.
PMID 23540223 - click here to show this article in PubMed
  FULL TEXT STATS

Recommend this article to:

Name:
E-mail:
From:
Language:


Related articles in IndexCopernicus™
     place of residence [7 related records]
     Education [1641 related records]
     Lithium [54 related records]
     Magnesium [201 related records]
     Depression [1258 related records]



 

Related articles

M Kustosz-Piątosa ,
VOICE EMISSION IN POPULAR SINGING, OR FROM TALKING...
Popular singing is a prolongation of talking with the use of emission and articulation techniques, closely cooperating with emotions and expression, conveyed with the word and music. The singer will achieve truth only when they sing with pleasure and...
ABSTRACT
S HOSSEINI, A MOHSENI BAND PEY,
 ...
 ...
ABSTRACT
S Seyed Hosseini, A Mardanshahi,
Depression and Glycemic Control in Type II Diabeti...
Objective: Studies reported conflicting results’ regarding the status of depression and glycemic control in patients with type II diabetes(T2DM), therefore, this study was performed to determine the relationship between depression and glycemic cont...
ABSTRACT