Twice malignant transformation of hypertrophic lichen planus

Dorota Krasowska 1, Katarzyna Kozłowicz 1, Małgorzata Kowal 1, Andrzej Kurylcio 2, Jolanta Budzyńska-Włodarczyk 3, Wojciech Polkowski 2, Grażyna Chodorowska 1
1 - Department of Dermatology, Venereology and Pediatric Dermatology, Medical University, Lublin, Poland
2 - Department of Surgical Oncology, Medical University, Lublin, Poland
3 - Regional Centre for Blood Donation and Haemotherapy – Local Branch in Zamosc, Poland
Ann Agric Environ Med
2012; 19 (4):
ICID: 1024108
Article type: Case report
Lichen planus is a chronic mucocutaneous T-cell-mediated disease, the cause of which remains unknown. The first case of lichen planus that transformed into squamous cell carcinoma was reported in 1903. The presented study concerns the case of a 62-year-old woman in whom twice malignant transformation of hypertrophic lichen planus in the dorsal part of the left foot developed. Several studies have pointed out the malignant transformation potential of lichen planus. Epidemiological studies from the last 20 years have revealed a malignant transformation rate of 0.27% per year, emphasizing the importance of the clinical follow-up of lichen planus patients.
PMID 23311808 - click here to show this article in PubMed

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