Alcohol-containing mouthwash and oral cancer – can epidemiology prove the absence of risk?
Dirk W. Lachenmeier 1 1 - Chemical and Veterinary Investigation Agency Karlsruhe, Germany Ann Agric Environ Med 2012; 19 (3): ICID: 1011054 Article type: Letter/Correspondence
Gandini et al.  are to be commended for providing the most detailed meta-analysis of epidemiological studies about the connection between mouthwash use and oral cancer risk.
The result (i.e. the absence of an association between use of alcohol-containing mouthwash and risk) was not completely unexpected, based on previous meta analyses financed by manufacturers of this type of mouthwash [2, 3, 4, 5], which were critically scrutinized in the past as the outcomes were often more favourable than in independently financed studies . Nevertheless, no obvious industry bias was recognizable in the current piece and, especially, the authors have clearly separated alcohol-containing from alcohol-free mouthwashes in their analysis.
PMID 23020065 - click here to show this article in PubMed