Efficacy and safety of insulin pump treatment in adult T1DM patients – influence of age and social environment

Małgorzata Grzanka 1, Bartłomiej Matejko 1, Katarzyna Cyganek 2, Elżbieta Kozek 2, Maciej T. Małecki 2, Tomasz Klupa 2
1 - Department of Metabolic Diseases, Jagiellonian University Medical College, Krakow, Poland
2 - Department of Metabolic Diseases, Jagiellonian University Medical College, Krakow, Poland; University Hospital, Krakow, Poland
Ann Agric Environ Med
2012; 19 (3):
ICID: 1010947
Article type: Short communication
Introduction and objective. Continuous subcutaneous insulin infusion (CSII) via personal insulin pump is a valuable therapeutic tool in T1DM patients. However, adherence to recommended CSII- related behaviours may be of concern to young adults with intensive, variable daily activities (students, young professionals). The aim of this observational study was to estimate treatment outcomes in young adult patients with T1DM, and compare them with older individuals.
Materials and methods. Overall, 140 adults with T1DM on CSII were examined, divided into 2 subgroups: 77 patients younger than 26 years of age (mean 20.6 years) and 63 older subjects (mean 39.0). We compared the glycaemic control in both groups of T1DM subjects and analyzed treatment attitudes to identify potentially modifiable behaviours influencing the efficacy of the treatment.
Results. The younger individuals were characterized by significantly worse treatment outcomes, compared to the older ones: the mean HbA1c levels were 7.6 ± 1.3% and 6.9±1.3% (p=0.00001), while the mean glucose levels based on glucometer downloads were 161±33.6 mg/dL and 136±21.8 mg/dL (p=0.00001), respectively. The frequency of self-monitoring of blood glucose (SMBG) was lower in younger individuals (5.3±2.1 vs. 7.0±2.8 daily, p=0.0005, respectively); they were also less frequently used advanced pump functions, e.g. the bolus calculator (48% vs. 67% users, p=0.0014, respectively).
Conclusions. The efficacy of CSII treatment observed in young T1DM adults was worse than in older patients. The reason for this phenomenon remains unclear, it may be due simply to age-dependend behaviours, to social environment, or both.
PMID 23020059 - click here to show this article in PubMed

Recommend this article to:


Related articles in IndexCopernicus™
     insulin pump [7 related records]
     continuous subcutaneous insulin infusion [9 related records]
     diabetes [966 related records]


Related articles

M Tekin, O Evliyaoğlu,
25-Hidroksivitamin D3 Düzeyleri Diyabetin Kontrol...
Amaç: Çalışmamız hemoglobin A1c (HbA1c) ile serum 25-hidroksi vitamin düzeyleri arasındaki ilişkiyi incelemek ve cinsiyete bağlı olası farklılıkları araştırmak için planlandı. Yöntemler: Bu çalışmada 660 erkek, 3015 kadın olma...
V Yurevich,
Membrane trophic effect of hyperglycemia on the an...
Introduction. Although there is a significant progress in the treatment of diabetic ocular complications, the issue of prevention and therapy for this pathology is still unstudied. The purpose of the present study was to study the stability of lyso...
H Abozaid,
Working with families who have school-age children...
Families of school-age children who suffer from type 1 diabetes are always in need of a special care and support. Reaching of diabetic control in those children without having hypoglycemia or limitating their daily activities have a burly emotion...